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i wouldn't worry about the plugs or coils to start, because if it's a random misfire, it's something that's messing with random cylinders.
i would most definitely check ALL rubber hoses and inspect them for small cracks and what not. when it's cold things will shrink, so those hoses will get small and will leak. then when they get warmed up, a small tiny leak could get covered up just by the hose expanding due to the heat. a vacuum leak will most certainly cause a random misfire.
Last edited by DrSheldonCooper; 12-10-2012 at 08:30 PM.